On 12 February 2022, the Director of Department of Vector Control at the Ministry of Health of Gedaref State, released an appeal statement calling for assistance in control of alarming increase in cases of Visceral Leishmaniasis (KalAzar). The report indicated a continuous increase of cases throughout 2022 with 302 cases and 8 death only for January compare to the previous year's showing cumulative data of 2,973 cases with 69 deaths registered in 2021; 2,136 cases with 38 deaths in 2020 and 2,098 cases with 29 death in 2019. Especially for children, there has been an alarming increase of cases with an average increase of 130% of cases and death. 24% of the reported cases were children since 2019. The report did not differentiate the type of leishmaniasis infections for the moment, which have 3 variants include Kal-Azar (the visceral mortal one), Cutaneous and Mucocutaneous. Base on the level of mortality, heath disagnostic, mortality increase can find their origin in the increase of the worst variant, the Kal-azar one. The risk for population and the humanitarian emergency on the spread of this disease become then an emergency scaled-up by local authorities and SRCS.